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Siglec-2/CD22: Products

Siglec-2 (sialic acid binding Ig-like lectin 2), also known as CD22, is a 130-140 kDa type I transmembrane glycoprotein with seven Ig-like domains in the extracellular region and three ITIM motifs in its cytoplasmic region. Alternate splicing generates an additional isoform that lacks the third and fourth Ig-like domains. Siglec-2 is expressed on B cells, preferentially binds alpha 2-6 linked sialic glycans including CD45 and mediates B cell - B cell interactions. Phosphorylation of Tyr822 within one of the ITIMs is important for Siglec-2 signal transduction through its association with the kinases Lyn, PI 3-Kinase p85 alpha, and SYK.

Showing 1-14 out of 14 Siglec-2/CD22 Products

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Recombinant Human Siglec-2/CD22 Fc Chimera Protein, CF

 1968-SL2  
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Mouse Siglec-2/CD22 Antibody

B/N, ICC/IF, WBAF22961  
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Human Phospho-Siglec-2/CD22 (Y822) Antibody

ICC/IF, WBMAB7290 
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Human Siglec-2/CD22 PE-conjugated Antibody

FlowFAB1968P1  
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Human Siglec-2/CD22 Antibody

WBMAB19681 
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Human Siglec-2/CD22 Antibody

Flow, ICC/IFMAB1968 
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Recombinant Mouse Siglec-2/CD22 Fc Chimera Protein, CF

 2296-SL 
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Mouse Siglec-2/CD22 Fluorescein-conjugated Antibody

FlowFAB2296F 
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Mouse Siglec-2/CD22 APC-conjugated Antibody

FlowFAB2296A 
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Mouse Siglec-2/CD22 Antibody

Flow, WBMAB2296 
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Mouse Siglec-2/CD22 PE-conjugated Antibody

FlowFAB2296P 
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Human Siglec-2/CD22 Fluorescein-conjugated Antibody

FlowFAB1968F 
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Human Siglec-2/CD22 (NP_001762) VersaClone cDNA

RDC1552 
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Proteome Profiler Human Phospho-Immunoreceptor Array Kit


Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
ARY004B2  
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