Skp2: Products

SKP2 (S-phase kinase-associated protein 2) is a 45-47 kDa cyclin A- and CDK2-associated phosphoprotein within the FBXL (F-box/LRR) family of ubiquitin ligases, designated FBXL1. As a component of the SCF (SKP1-Cul1-F-box) complex, SKP2 phosphorylation is required for degradation of CDK inhibitors such as p27/Kip1 and progression from G1 to S phases of the cell cycle. Deregulation in cancer promotes cell cycle progression and cancer growth.

Showing 1-4 out of 4 Skp2 Products

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SZL P1-41


Selective Skp2 inhibitor; suppresses E3 ligase activity
5076 
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Human Skp2 Antibody

WBMAB6817 
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Human Skp2 Antibody

WBAF6817 
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SKPin C1


Inhibits Skp2-mediated p27 degradation; induces cell cycle arrest
4817 
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