Soggy-1/DkkL1: Products

Members of the dickkopf-related protein family (Dkk-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. Dkk-3 and -4 also have one prokineticin domain. Dkk-1, -2, and -4 function as antagonists of canonical Wnt signaling by binding to LRP5/6, preventing interaction of LRP5/6 with Wnt-Frizzled complexes. Dkk-1, -2, and -4 also bind cell surface Kremen-1 or -2 and promote the internalization of LRP5/6. Antagonistic activity of Dkk-3 has not been demonstrated. Dkk proteins have distinct patterns of expression in adult and embryonic tissues and have a wide range of effects on tissue development and morphogenesis. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear.

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Mouse Soggy-1/DkkL1 Antibody

WBAF15082  
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Mouse Soggy-1/DkkL1 Antibody

WBMAB15081  
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Recombinant Human Soggy-1/DkkL1 Protein

 1549-S12  
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Recombinant Human Soggy-1/DkkL1 Protein, CF

 1549-S1/CF2  
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Mouse Soggy-1/DkkL1 Biotinylated Antibody

WBBAF1508 
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Human Soggy-1/DkkL1 Biotinylated Antibody

WBBAF1549 
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Human Soggy-1/DkkL1 Antibody

WBAF1549 
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Human Soggy-1 Antibody

WBMAB1549 
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Recombinant Mouse Soggy-1/DkkL1 Protein, CF

 1508-S1/CF 
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Recombinant Mouse Soggy-1/DkkL1 Protein

 1508-S1 
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Mouse Soggy-1/DkkL1 DuoSet ELISA

ELISADY1508 
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