Sonic Hedgehog/Shh: Products

Shh (Sonic Hedgehog) is expressed in embryonic tissues that are critical for the patterning of the developing central nervous system, somite, and limb. It is also involved in whisker, hair, foregut, tooth, and bone development. Shh regulates neural and hematopoietic stem cell fate and is important for thymocyte differentiation and proliferation. In adult tissue Shh is associated with cancer development and tissue remodeling following injury. Palmitoylation and cholesterol addition of Shh contribute to its membrane tethering and assembly into multimers. Lipid modification and multimerization greatly increase Shh signaling potency. Shh can be released from the plasma membrane by the cooperative action of DISP1, SCUBE2, and TACE/ADAM17. Canonical signaling of Shh is mediated by a receptor complex that includes Patched (PTCH1, PTCH2) and Smoothened (SMO).

Showing 1-24 out of 24 Sonic Hedgehog/Shh Products

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Recombinant Human Sonic Hedgehog/Shh (C24II) N-Terminus, CF

 1845-SH/CF6  
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Recombinant Human Sonic Hedgehog/Shh (C24II) N-Terminus

 1845-SH6  
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Recombinant Mouse Sonic Hedgehog/Shh (C25II) N-Terminus, CF

 464-SH/CF9  
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Recombinant Mouse Sonic Hedgehog/Shh (C25II) N-Terminus

 464-SH9  
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Recombinant Mouse Sonic Hedgehog/Shh, N-Terminus Protein, CF

 461-SH/CF21  
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Recombinant Mouse Sonic Hedgehog/Shh, N-Terminus Protein

 461-SH21  
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Recombinant Human Sonic Hedgehog/Shh, N-Terminus Protein

 1314-SH6  
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Recombinant Human Sonic Hedgehog/Shh, N-Terminus Protein, CF

 1314-SH/CF6  
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Human/Mouse Sonic Hedgehog/Shh N‑Terminus Antibody

IHC, WBAF4648  
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Mouse Sonic Hedgehog/Shh N-Terminus Antibody

B/N, ELISA(Cap), IHC, WBMAB46412  
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Recombinant Human Sonic Hedgehog/Shh, N-Terminus GMP, CF


Animal-Free
 1314-GMP 
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Mouse Sonic Hedgehog/Shh C-Terminus Antibody

IHC, WBAF4455  
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Human Sonic Hedgehog/Shh N-Terminus Quantikine ELISA Kit

ELISADSHH00 
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Recombinant Human Sonic Hedgehog Protein, High Activity, CF


C-terminal cholesterol, N-terminal fatty acid-modified
 8908-SH/CF 
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Recombinant Human Sonic Hedgehog/Shh Protein, High Activity


C-terminal cholesterol, N-terminal fatty acid-modified
 8908-SH 
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Mouse Sonic Hedgehog/Shh DuoSet ELISA

ELISADY4615  
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Human/Mouse Sonic Hedgehog N‑Terminus Antibody

WBMAB4642  
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Human/Mouse Sonic Hedgehog/Shh N-Terminus PE-conjugated Antibody

FlowIC4641P2  
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Recombinant Human Sonic Hedgehog/Shh (C24II) N-Term GMP, CF


Animal-Free
 1845-GMP 
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Mouse Sonic Hedgehog/Shh N-Terminus Quantikine ELISA Kit

ELISAMSHH001  
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Mouse Sonic Hedgehog/Shh N-Terminus Biotinylated Antibody

BAM46421  
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Mouse Sonic Hedgehog/Shh C-Terminus Biotinylated Antibody

WBBAF445 
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Mouse Sonic Hedgehog/Shh C-Terminus Antibody

WBMAB445 
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Quantikine Immunoassay Control Set 882 for Human Shh-N


For use with catalog number DSHH00
CtrlQC219 
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