Synthetic Metalloprotease Inhibitors: Products

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

Showing 1-24 out of 24 Synthetic Metalloprotease Inhibitors Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

GI 254023X


Selective ADAM10 metalloprotease inhibitor
39955
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Doxycycline hyclate


Broad-spectrum MMP inhibitor; tetracycline derivative
40901
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Batimastat


Potent, broad spectrum MMP inhibitor
296126
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Minocycline hydrochloride


Antibiotic. Displays neuroprotective effects
32682
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Marimastat


Broad spectrum MMP inhibitor
263119
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

GM 6001


Broad spectrum MMP inhibitor
29837
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

NSC 405020


Inhibitor of MT1-MMP; antitumor
49021
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CL 82198 hydrochloride


Selective inhibitor of MMP-13
26323
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

WAY 170523


Potent and selective inhibitor of MMP-13
2633
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TAPI 0


ADAM-17 (TACE) and MMP inhibitor
5523
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TAPI 2


ADAM-17 (TACE) and MMP inhibitor
6013
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SB 3CT


Selective high affinity MMP2 inhibitor
6088
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

PD 166793


Broad spectrum MMP inhibitor
2520
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ARP 100


Selective inhibitor of MMP-2
26213
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ARP 101


Inhibitor of MMP-2
26223
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ONO 4817


Broad spectrum MMP inhibitor
2628
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

UK 370106


Highly selective MMP-3 and MMP-12 inhibitor
29001
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CP 471474


Broad spectrum MMP inhibitor
37803
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

UK 356618


Potent and selective MMP-3 inhibitor
41871
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

UK 383367


Potent and selective BMP-1 (PCP) inhibitor
4188
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SD 2590 hydrochloride


Potent MMP inhibitor
4775
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TMI 1


Adam 17 (TACE) and MMP inhibitor; orally bioavailable
5960
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

T 26c disodium salt


Highly potent and selective MMP13 inhibitor
6134
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TAPI 1


ADAM-17 (TACE) and MMP inhibitor
6162
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page