T-bet/TBX21: Products

T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.

Showing 1-5 out of 5 T-bet/TBX21 Products

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Human T-bet/TBX21 Antibody

Flow, ICC/IF, WBMAB53853  
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Human T-bet/TBX21 Alexa Fluor® 488-conjugated Antibody


Recombinant Monoclonal Antibody.
FlowIC53851G 
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Human T-bet/TBX21 PerCP-conjugated Antibody

FlowIC5385C1  
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Human T-bet/TBX21 Antibody


Recombinant Monoclonal Antibody.
FlowMAB53851 
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Human T-bet/TBX21 Fluorescein-conjugated Antibody

FlowIC5385F 
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