TCF7/TCF1: Products

TCF7 (Transcription factor 7; also T cell factor 1/TCF1) is a 25 - 50 kDa member of the lymphoid enhancer binding factor family of proteins with 16 isoforms. It is expressed in thymocytes and mature T cells, and serves multiple purposes. In resting cells, TCF family members are transcriptional repressors, and are 25 - 32 kDa in size. Following activation, large TCF7 isoforms predominate (42 - 50 kDa), and serve a transcriptional activator function. Human TCF7 is 384 amino acids (aa) in length. This is likely an activating isoform that contains a beta-Catenin binding domain (aa 1 - 59), a DNA-binding HMG-box (aa 269 - 337), and an NLS (aa 344 - 348). The use of an alternate start site at Met116 seems to characterize repressor isoforms.

Showing 1-4 out of 4 TCF7/TCF1 Products

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Human TCF7/TCF1 Antibody

ICC/IF, IHC, WBAF5596 
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Mouse TCF7/TCF1 Antibody

Flow, WBMAB8224 
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Mouse TCF7/TCF1 Alexa Fluor® 488-conjugated Antibody

FlowIC8224G 
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Mouse TCF7/TCF1 PE-conjugated Antibody

FlowIC8224P 
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