TGF-beta RIII: Products

Most cell types express three sizes of receptors for TGF-beta. These are designated Type I (53 kDa), Type II (70 - 85 kDa), and Type III (250 - 350 kDa). The Type I receptor is a membrane-bound serine/threonine kinase that apparently requires the presence of the Type II receptor to bind TGF-beta. The Type II receptor is also a membrane-bound serine/threonine kinase that binds TGF-beta1 and TGF-beta 3 with high affinity and TGF-beta 2 with much lower affinity. The Type I and Type II receptors together form a heterodimeric signaling complex that is essential for the transduction of the anti-proliferative signals of TGF-beta. The Type III receptor is a transmembrane proteoglycan with a large extracellular domain and a 43 amino acid residue cytoplasmic domain. The cytoplasmic domain of the Type III receptor lacks an obvious signaling motif and the receptor may not be involved directly in signal transduction.

Showing 1-14 out of 14 TGF-beta RIII Products

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Human TGF-beta  RIII Antibody

Flow, WBAF-242-PB6  
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Recombinant Human TGF-beta RIII Protein

 242-R34  
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Recombinant Human TGF-beta RIII Protein, CF

 242-R3/CF4  
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Human TGF-beta  RIII Biotinylated Antibody

ELISA(Det), WBBAF2421  
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Human TGF-beta  RIII Fluorescein-conjugated Antibody

FlowFAB242F1  
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Human TGF-beta  RIII PE-conjugated Antibody

FlowFAB242P1  
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Mouse TGF-beta RIII Biotinylated Antibody

WBBAF5034 
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Human TGF-beta RIII DuoSet ELISA

ELISADY2421  
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Human TGF-beta  RIII Antibody

WBMAB242 
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Human TGF-beta  RIII Antibody

MAB2421 
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Mouse TGF-beta  RIII Antibody

WBAF5034 
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Mouse TGF-beta RIII (NP_035708) VersaClone cDNA

RDC1363 
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Human TGF-beta RIII (NP_003234) VersaClone cDNA

RDC1421 
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Recombinant Mouse TGF-beta RIII Protein, CF

 5034-R3 
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