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TIM-3: Products

TIM-3 (T cell immunoglobulin and mucin domain-3), also known as HAVCR2 is an immunosuppressive protein that enhances tolerance and inhibits anti-tumor immunity. It is upregulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). TIM-3 ligation by Galectin-9 attenuates CD8+ and Th1 cell responses and promotes the activity of Treg and myeloid derived suppressor cells. Dendritic cell-expressed TIM-3 dampens inflammation by enabling the phagocytosis of apoptotic cells and the cross-presentation of apoptotic cell antigens. TIM-3 also binds the alarmin HMGB1, thereby preventing the activation of TLRs in response to released tumor cell DNA.

Showing 1-30 out of 30 TIM-3 Products

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DescriptionApplicationCat#CitationsImages 

Recombinant Human TIM-3 Fc Chimera Protein, CF

 2365-TM5  
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Human TIM-3 PE-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365P15  
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Human TIM-3 Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowMAB23655  
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Human TIM-3 APC-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365A5  
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Human TIM-3 Antibody

Flow, WBAF23658  
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Recombinant Mouse TIM-3 Fc Chimera Protein, CF

 1529-TM 
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Mouse TIM-3 PE-conjugated Antibody

FlowFAB1529P3  
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Human TIM-3 Alexa Fluor® 488-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365G2  
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Mouse TIM-3 Alexa Fluor® 488-conjugated Antibody

FlowFAB1529G 
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Recombinant Cynomolgus Monkey TIM-3 Fc Chimera Protein, CF

 7914-TM 
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Human TIM-3 Antibody

FuncMAB236511  
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Human TIM-3 Biotinylated Antibody

Flow, WBBAF23651  
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Mouse TIM-3 Antibody

Flow, WBAF15292  
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Mouse TIM-3 APC-conjugated Antibody

FlowFAB1529A2  
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Human TIM-3 Alexa Fluor® 700-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365N1  
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Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B5  
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Mouse TIM-3 Antibody

WBMAB152911  
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Human TIM-3 Quantikine ELISA Kit

ELISADTIM30 
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Human TIM-3 PerCP-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365C2  
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Human TIM-3 Alexa Fluor® 647-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365R 
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Human TIM-3 Alexa Fluor® 750-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365S 
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Human TIM-3 Alexa Fluor® 594-conjugated Antibody


Clone 344823 was used by HLDA to establish CD designation
FlowFAB2365T 
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Mouse TIM-3 PerCP-conjugated Antibody

FlowFAB1529C 
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Mouse TIM-3 Biotinylated Antibody

WBBAF1529 
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Mouse TIM-3 (AAL65156) VersaClone cDNA

RDC0787 
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Cynomolgus Monkey TIM-3 (XP_005558438) VersaClone cDNA

RDC1698 
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Human TIM-3 DuoSet ELISA

ELISADY2365 
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Human TIM-3 (AAL65157) VersaClone cDNA

RDC0670 
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Quantikine Immunoassay Control Set 887 Human TIM-3


For use with catalog number DTIM30
CtrlQC217 
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Proteome Profiler Human sReceptor Array, Hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 48 different hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY0111  
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