TIMP Assay Kits: Products

TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

Showing 1-2 out of 2 TIMP Assay Kits Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human TIMP Luminex Performance Assay 4-plex Kit


For the measurement of TIMP-1, TIMP-2, TIMP-3 and TIMP-4
LKT0038  
View Sizes & Prices
Build your own with our Luminex Assay Customization Tool.

Human TIMP Magnetic Luminex Performance Assay 4-plex Kit


For the measurement of TIMP-1, TIMP-2, TIMP-3 and TIMP-4
LKTM0032  
View Sizes & Prices
Build your own with our Luminex Assay Customization Tool.
page of 1
Results Per Page