TLR1: Products

TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.

Showing 1-16 out of 16 TLR1 Products

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Pam3CSK4


TLR1/2 agonist; induces cytokine production
4633 
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Human TLR1 Biotinylated Antibody

WBBAF14841  
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CU CPT 22


Selective TLR1/2 inhibitor
48841  
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Human TLR1 APC-conjugated Antibody

FlowFAB1484A1  
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Recombinant Human TLR1 Fc Chimera Protein, CF

 1484-TR1  
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Human TLR1 PE-conjugated Antibody

FlowFAB1484P 
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Mouse TLR1 PE-conjugated Antibody

FlowFAB1475P 
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Human TLR1 Antibody

Flow, WBAF1484 
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Mouse TLR1 Antibody

Flow, WBAF1475 
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Mouse TLR1 Biotinylated Antibody

Flow, WBBAF1475 
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Mouse TLR1 Antibody

WBMAB1475 
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CU-T12-9


Potent TLR1/2 agonist
5414 
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Pam3CSK4 Biotin


Biotinylated Pam3CSK4 (Cat. No. 4633)
4636 
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Recombinant Mouse TLR1 Protein, CF

 1476-TR 
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Human TLR1 (NP_003254) VersaClone cDNA

RDC0442 
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Mouse TLR1 (NP_109607) VersaClone cDNA

RDC0613 
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