TLR7: Products

TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.

Showing 1-12 out of 12 TLR7 Products

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Human TLR7 PE-conjugated Antibody

FlowIC5875P 
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Resiquimod


Toll-like receptor 7 (TLR7) agonist
4536 
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Human TLR7 Alexa Fluor® 488-conjugated Antibody

FlowIC5875G 
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Mouse/Rat TLR7 Antibody

WBMAB7156 
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Human TLR7 PerCP-conjugated Antibody

FlowIC5875C 
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Human TLR7 Antibody

FlowMAB5875 
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Imiquimod


Toll-like receptor 7 (TLR7) agonist
3700 
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SM 324405


Potent TLR7 agonist
5445 
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RWJ 21757


Toll-like receptor 7 (TLR7) agonist
2719 
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DSR 6434


Potent TLR7 agonist
4809 
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Human TLR7 (NP_057646) VersaClone cDNA

RDC0640 
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Mouse TLR7 (NP_573474) VersaClone cDNA

RDC0738 
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