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TNF-alpha: Products

TNF-alpha (Tumor necrosis factor alpha) plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism. It is produced by a wide variety of immune, epithelial, endothelial, and tumor cells. Cell surface trimeric TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells. Shedding of membrane bound TNF-alpha by TACE (ADAM17) releases the bioactive cytokine. TNF-alpha binds TNF RI and TNF RII and induces apoptotic signaling through the death domain of TNF RI.

Showing 1-10 out of 10 TNF-alpha Products

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LXSAHM1  
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LUH21050  
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LXSAMSM 
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LXSAH 
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LHSCM2101  
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LXSAMS 
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LHSC2101  
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LXSARM 
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LUHM210 
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LXSAR1  
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