TNF-alpha: Products

TNF-alpha (Tumor necrosis factor alpha) plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism. It is produced by a wide variety of immune, epithelial, endothelial, and tumor cells. Cell surface trimeric TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells. Shedding of membrane bound TNF-alpha by TACE (ADAM17) releases the bioactive cytokine. TNF-alpha binds TNF RI and TNF RII and induces apoptotic signaling through the death domain of TNF RI.

Showing 1-34 out of 34 TNF-alpha Products

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Recombinant Human TNF-alpha Protein

 210-TA308  
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Recombinant Human TNF-alpha Protein, CF

 210-TA/CF308  
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Recombinant Mouse TNF-alpha (aa 80-235) Protein, CF

 410-MT/CF144  
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Recombinant Mouse TNF-alpha (aa 80-235) Protein

 410-MT144  
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Recombinant Rat TNF-alpha Protein, CF

 510-RT/CF37  
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Recombinant Rat TNF-alpha Protein

 510-RT37  
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Recombinant Human TNF-alpha GMP Protein, CF


Animal-Free
 210-GMP 
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Recombinant Human TNF-alpha, Animal-Free Protein

 AFL210 
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Recombinant Human TNF-alpha, Biotinylated Protein, CF

 BT210/CF 
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Recombinant Human TNF-alpha, Biotinylated Protein

 BT210 
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Recombinant Porcine TNF-alpha Protein

 690-PT5  
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Recombinant Porcine TNF-alpha Protein, CF

 690-PT/CF5  
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Recombinant Canine TNF-alpha Protein, CF

 1507-CT/CF3  
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Recombinant Mouse TNF-alpha (aa 84-235) Protein

 410-TRNC3  
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Recombinant Mouse TNF-alpha (aa 84-235) Protein, CF

 410-TRNC/CF3  
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Recombinant Canine TNF-alpha Protein

 1507-CT3  
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Recombinant Bovine TNF-alpha Protein

 2279-BT4  
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Recombinant Bovine TNF-alpha Protein, CF

 2279-BT/CF4  
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Recombinant Equine TNF-alpha Protein

 1814-ET1  
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Recombinant Equine TNF-alpha Protein, CF

 1814-ET/CF1  
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Recombinant Rhesus Macaque TNF-alpha Protein

 1070-RM1  
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Recombinant Rhesus Macaque TNF-alpha Protein, CF

 1070-RM/CF1  
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Recombinant Rabbit TNF-alpha Protein, CF

 5670-TG/CF 
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Recombinant Guinea Pig TNF-alpha Protein

 5035-TG 
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Recombinant Rabbit TNF-alpha Protein

 5670-TG 
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Recombinant Guinea Pig TNF-alpha Protein, CF

 5035-TG/CF 
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Recombinant Human TNF-alpha Hyperactive Mutant Protein


Mutant form with approximately 5-fold greater activity
 8599-TA 
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Recombinant Cotton Rat TNF-alpha Protein

 1011-CR 
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Recombinant Mouse TNF-alpha, Animal-Free Protein

 AFL410 
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Recombinant Feline TNF-alpha Protein, CF

 2586-FT/CF 
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Recombinant Human TNF-alpha Hyperactive Mutant Protein, CF


Mutant form with approximately 5-fold greater activity
 8599-TA/CF 
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Recombinant Pro-TNF-alpha Fusion Protein, CF

 1012-PS 
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Recombinant Cotton Rat TNF-alpha Protein, CF

 1011-CR/CF 
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Recombinant Feline TNF-alpha Protein

 2586-FT 
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