TRAIL R2/TNFRSF10B: Products

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members.

TRAIL binds at least five different receptors: TRAIL R1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAIL R1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis. The remaining receptors are decoys that may regulate TRAIL activity by competing for binding sites with TRAIL R1 and R2. TRAIL R3 is membrane-associated via GPI linkage. TRAIL R4 is a type 1 transmembrane receptor, but exhibits a truncated cytoplasmic domain. Like the active receptors TRAIL R1 and R2, OPG has a DD motif but is a soluble protein.

Showing 1-16 out of 16 TRAIL R2/TNFRSF10B Products

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Human TRAIL R2/TNFRSF10B Antibody

Func, WBAF63122  
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Human TRAIL R2/TNFRSF10B PE-conjugated Antibody

FlowFAB6311P13  
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Human TRAIL R2/TNFRSF10B Antibody

CyTOF-ready, FlowMAB631114  
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Human TRAIL R2/TNFRSF10B Antibody

FuncMAB6315  
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Mouse TRAIL R2/TNFRSF10B Antibody

B/N, CyTOF-ready, Flow, WBAF7213  
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Human TRAIL R2/TNFRSF10B Biotinylated Antibody

WBBAF6314  
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Mouse TRAIL R2/TNFRSF10B Antibody

IHC, WBMAB15401  
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Human TRAIL R2/TNFRSF10B Antibody

WBMAB6313 
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Human TRAIL R2/TNFRSF10B Alexa Fluor® 488-conjugated Antibody

FlowFAB6311G 
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Human TRAIL R2/TNFRSF10B APC-conjugated Antibody

FlowFAB6311A 
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Mouse TRAIL R2/TNFRSF10B Biotinylated Antibody

Flow, WBBAF7211  
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Human TRAIL R2/TNFRSF10B Alexa Fluor® 647-conjugated Antibody

FlowFAB6311R 
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Mouse TRAIL R2/TNFRSF10B APC-conjugated Antibody

FlowFAB721A 
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Human TRAIL R2/TNFRSF10B Alexa Fluor® 700-conjugated Antibody

FlowFAB6311N 
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Human TRAIL R2/TNFRSF10B PerCP-conjugated Antibody

FlowFAB6311C 
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Mouse TRAIL R2/TNFRSF10B PerCP-conjugated Antibody

FlowFAB721C 
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