TRAIL R4/TNFRSF10D: Products

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members.

TRAIL binds at least five different receptors: TRAIL R1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAIL R1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis. The remaining receptors are decoys that may regulate TRAIL activity by competing for binding sites with TRAIL R1 and R2. TRAIL R3 is membrane-associated via GPI linkage. TRAIL R4 is a type 1 transmembrane receptor, but exhibits a truncated cytoplasmic domain. Like the active receptors TRAIL R1 and R2, OPG has a DD motif but is a soluble protein.

Showing 1-10 out of 10 TRAIL R4/TNFRSF10D Products

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Human TRAIL R4/TNFRSF10D Antibody

B/N, ELISA(Cap), Flow, WBMAB633 
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Human TRAIL R4/TNFRSF10D Antibody

B/N, Flow, IHC, WBAF633 
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Human TRAIL R4/TNFRSF10D PE-conjugated Antibody

FlowFAB633P 
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Human TRAIL R4/TNFRSF10D Biotinylated Antibody

ELISA(Det), WBBAF633 
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Recombinant Human TRAIL R4/TNFRSF10D Fc Chimera Protein, CF

 633-TR 
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Human TRAIL R4/TNFRSF10D PerCP-conjugated Antibody

FlowFAB633C 
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Human TRAIL R4/TNFRSF10D APC-conjugated Antibody

FlowFAB633A 
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Human TRAIL R4/TNFRSF10D Alexa Fluor® 488-conjugated Antibody

FlowFAB633G 
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Human TRAIL R4/TNFRSF10D (NP_003831) VersaClone cDNA

RDC1564 
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Human TRAIL R4/TNFRSF10D DuoSet ELISA

ELISADY633 
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