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TREM-2: Products

TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a transmembrane protein that is expressed on newly differentiated and alternatively activated tissue macrophages, immature myeloid dendritic cells, and osteoclasts. TREM-2 interacts with and modifies signaling through dendritic cell and osteoclast Plexin A1, a semaphorin receptor. It is active in several settings that involve membrane fusion, including phagocytosis of microbes by macrophages and apoptotic neurons by microglia, and formation of osteoclasts and multinucleated giant cells from macrophages. TREM-2 signals through the adaptor protein DAP12 and can associate with the linker protein LAT2 to inhibit macrophage activaation. A soluble isoform of TREM-2 antagonizes full-length TREM-2 and is elevated in cerebrospinal fluid of patients with active multiple sclerosis.

Showing 1-21 out of 21 TREM-2 Products

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Human/Mouse TREM-2 Antibody

FlowMAB172911  
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Human TREM-2 Antibody

Flow, ICC/IF, WBAF18283  
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Recombinant Human TREM-2 Fc Chimera Protein, CF

 1828-T2 
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Human/Mouse TREM-2 APC-conjugated Antibody

FlowFAB17291A 
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Human/Mouse TREM-2 PE-conjugated Antibody

FlowFAB17291P 
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Human TREM-2 Antibody

WBMAB18282  
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Mouse TREM-2 Antibody

ICC/IF, WBAF17292  
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Recombinant Mouse TREM-2 Fc Chimera Protein, CF

 1729-T24  
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Human TREM-2 Biotinylated Antibody

Flow, ICC/IF, WBBAF1828 
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Human/Mouse TREM-2 Alexa Fluor® 700-conjugated Antibody

FlowFAB17291N 
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Mouse TREM-2 Biotinylated Antibody

ICC/IF, WBBAF17291  
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Mouse TREM-2 Antibody

WBMAB17291  
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Human/Mouse TREM-2 Alexa Fluor® 647-conjugated Antibody

FlowFAB17291R 
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Human/Mouse TREM-2 PerCP-conjugated Antibody

FlowFAB17291C 
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Human/Mouse TREM-2 Alexa Fluor® 594-conjugated Antibody

FlowFAB17291T 
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Human/Mouse TREM-2 Alexa Fluor® 750-conjugated Antibody

FlowFAB17291S 
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Recombinant Human TREM-2 His-tag Protein, CF

 9256-T2 
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Recombinant Mouse TREM-2 His-tag Protein, CF

 9228-T2 
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Mouse TREM-2 (NP_112544) VersaClone cDNA

RDC0948 
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Human TREM-2 (NP_061838) VersaClone cDNA

RDC0861 
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Proteome Profiler Human Phospho-Immunoreceptor Array Kit


Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
ARY004B2  
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