Tankyrase Inhibitors: Products

PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.

Showing 1-6 out of 6 Tankyrase Inhibitors Products

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XAV 939


Potent tankyrase inhibitor
374815  
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WIKI4


Potent tankyrase inhibitor
4855 
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TC-E 5001


Potent tankyrase inhibitor
5049 
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JW 55


Tankyrase inhibitor
4514 
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MN 64


Potent and selective tankyrase inhibitor
5084 
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AZ 6102


Potent TNKS1/2 inhibitor
5775 
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