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TfR (Transferrin R): Products

Transferrin Receptor (TfR, TfR-1, CD71) is a transmembrane glycoprotein expressed on erythroid progenitors, muscle cells and proliferating cells as a disulfide-linked homodimer. As the major mediator of cellular iron uptake, it binds and internalizes diferric transferrin, allowing iron release at the low pH of the endosome. Proteolytic shedding of TfR into the circulation is enhanced by iron deficiency. The hereditary hemochromatosis protein HFE competes with diferric transferrin for binding to TfR and targets TfR for degradation rather than recycling. Cancer cells can express up to 5-fold more TfR than quiescent cells in the surrounding tissue. TfR carries out ferritin-independent functions in T cell development, immunological synapse formation and Galectin-3-mediated cell death, and it serves as a cell entry receptor for New World hemorrhagic fever arenaviruses.

Showing 1-14 out of 14 TfR (Transferrin R) Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Human sTfR Quantikine IVD ELISA Kit


For In Vitro Diagnostic Use
ELISADTFR120  
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Recombinant Human TfR Protein, CF

 2474-TR1  
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Human Luminex Assay

LXSAH4  
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Human TfR (Transferrin R) Antibody

B/N, IHC, WBAF24743  
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Human TfR (Transferrin R) Antibody

FlowMAB24742  
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Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B5  
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Rat TfR (Transferrin R) Alexa Fluor® 647-conjugated Antibody

FlowFAB9294R 
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Human TfR (Transferrin R) Biotinylated Antibody

WBBAF2474 
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Human TfR (Transferrin R) APC-conjugated Antibody

FlowFAB2474A 
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Human TfR (Transferrin R) PE-conjugated Antibody

FlowFAB2474P 
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Human TfR DuoSet ELISA

ELISADY2474 
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Human TfR (Transferrin R) (NP_003225) VersaClone cDNA

RDC1367 
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Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY027 
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