Thrombopoietin/Tpo: Products

Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.

Showing 1-9 out of 9 Thrombopoietin/Tpo Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 
B/N, WBAF-288-NA2  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
ELISA(Det), WBBAF288 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
B/N, ELISA(Cap)MAB2881  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
B/N, WBAF-488-NA1  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
BAM2881  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
ELISA(Det), WBBAF4881  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
B/N, WBAB-288-NA 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
WBMAB28811  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
ELISA(Cap), WBMAB488 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page