Filter Results

UBE2M/Ubc12: Products

Ubiquitin-conjugating Enzyme E2M (UBE2M), also known as Ubiquitin-conjugating Enzyme 12 (Ubc12), is a ubiquitously expressed protein with a predicted molecular weight of 20 kDa. UBE2M/Ubc12 is highly conserved, and the human ortholog shares 100% amino acid identity with mouse and rat UBE2M. UBE2M/Ubc12 mediates conjugation of the Ubiquitin-like protein Neural Precursor Cell Expressed, Developmentally Down-regulated 8 (NEDD8) to substrate proteins. Neddylation requires the coordinated activities of UBE2M/Ubc12 and the APPBPI/UBA3 heterodimer, a NEDD8-activating (E1) enzyme. The NEDD8 pathway is essential for the viability of many organisms and plays important roles in morphogenesis and cell cycle progression. UBE2M/Ubc12-dependent neddylation modulates the levels of p27/Kip1, beta-Catenin, Cdc53/Cul1, and other members of the Cullin family.

Showing 1-3 out of 3 UBE2M/Ubc12 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Recombinant Human UBE2M/Ubc12 Protein, CF

 E2-6561  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human UBE2M/Ubc12 Antibody

WBA-6551  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human GST-UBE2M/Ubc12 Protein, CF

 E2-655 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page