UNC5H2/UNC5B: Products

UNC5H2/UNC5B is a transmembrane molecule that mediates axon repulsion and growth cone collapse through interactions with Netrin, Neogenin, and FLRT3. Its association with DCC switches the DCC-Netrin-1 response from attraction to repulsion. Outside the nervous system, UNC5H2 facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration as well as Netrin-1-mediated promotion of osteoclast differentiation. It is downregulated in multiple cancers and inhibits tumor cell growth and invasion. It also plays a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury.

Showing 1-6 out of 6 UNC5H2/UNC5B Products

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Rat UNC5H2/UNC5B Antibody

IHC, WBAF10066  
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Recombinant Rat UNC5H2/UNC5B Fc Chimera Protein, CF

 1006-UN1  
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Rat UNC5H2/UNC5B Biotinylated Antibody

IHC, WBBAF1006 
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Rat UNC5H2/UNC5B Antibody

WBMAB10061  
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Recombinant Human UNC5B Protein Fc Chimera, CF

 8869-UN 
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Human UNC5H2/UNC5B (NP_734465) VersaClone cDNA

RDC1777 
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