UbcH5a/UBE2D1: Products

Ubiquitin-conjugating Enzyme H5a (UbcH5a), also known as Ubiquitin-conjugating Enzyme E2D 1 (UBE2D1), is a ubiquitously expressed protein that is related to Stimulator of Iron Transport (SFT). Human UbcH5a/UBE2D1 has a predicted molecular weight of 17 kDa and shares 89% and 88% amino acid (aa) sequence identity with the related family members UbcH5b and UbcH5c, respectively. Human UbcH5a/UBE2D1 shares 100% aa sequence identity with the mouse and rat orthologs. UbcH5a/UBE2D1 has a conserved E2 catalytic core domain that contains an active site cysteine residue, and it interacts with a variety of HECT and RING finger Ubiquitin ligases (E3) to mediate the ubiquitination of specific target proteins. UbcH5a/UBE2D1 interacts with the E3, E6-AP, to conjugate Ubiquitin to the tumor suppressor, p53. Additional protein targets of UbcH5a/UBE2D1 include c-Fos, RIP1, and HIF-1. Pathologically, UbcH5a/UBE2D1 is implicated in protein degradation during cancer and immune responses.

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Recombinant Human UbcH5a/UBE2D1 Protein, CF

 E2-6167  
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Human UbcH5/UBE2D Antibody

WBA-6152  
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Recombinant Human GST-UbcH5a/UBE2D1 Protein, CF

 E2-6152  
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Recombinant Human UbcH (E2) Enzyme Set Protein


Contains 10 ug each of rhUbcH2/UBE2H, rhHis6-UbcH3/Cdc34, rhUbcH5a/UBE2D1, rhUbcH5b/UBE2D2, rhUbcH5c/UBE2D3, rhHis6-UbcH6/UBE2E1, rhUbcH7/UBE2L3, rhHis6-UBE2E3, rhUbcH10/UBE2C, and rhHis6-UbcH13/Uev1a Complex
K-980B 
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Recombinant Human UbcH5a/UBE2D1 - Ubiquitin Charged Protein

 E2-800 
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