Ubiquitin Ligase (E3) Inhibitors

Showing 1-18 out of 18 Ubiquitin Ligase (E3) Inhibitors Products

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proTAME


Cell-permeable APC/C inhibitor
I-4404  
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Apcin


Cell-permeable APC/C Inhibitor
I-444 
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Nutlin-3


MDM2 antagonist; inhibits MDM2-p53 interaction
39841  
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SZL P1-41


Selective Skp2 inhibitor; suppresses E3 ligase activity
5076 
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Heclin


HECT E3 ubiquitin ligase inhibitor
5433 
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PRT 4165


Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination
5047 
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A01


High affinity Smurf1 inhibitor; enhances BMP signaling
5397 
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Apcin


Cdc20 inhibitor; inhibits Cdc20-substrate interaction
5747 
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HLI 373


Hdm2 inhibitor; activates p53-dependent transcription
3503 
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SKPin C1


Inhibits Skp2-mediated p27 degradation; induces cell cycle arrest
4817 
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RITA


MDM2-p53 interaction inhibitor
24431  
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SMER 3


Selective inhibitor of E3 ubiquitin ligase
4375 
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SP 141


High affinity MDM2 inhibitor
5332 
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PTC 209


Bmi-1 inhibitor; antitumor
5191 
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GS 143


beta-TrCP1 ligase inhibitor
5636 
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NAB 2


Protects against alpha-synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport
5131 
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TAME hydrochloride


Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination
45061  
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NSC 66811


MDM2 antagonist. Disrupts MDM2-p53 interaction
2936 
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