Ubiquitin+1: Products

Ubiquitin is a 76 amino acid (aa) protein that is ubiquitously expressed in all eukaryotic organisms. Ubiquitin is highly conserved with 96% aa sequence identity shared between human and yeast Ubiquitin, and 100% aa sequence identity shared between human and mouse Ubiquitin. In mammals, four Ubiquitin genes encode for two Ubiquitin-ribosomal fusion proteins and two poly-Ubiquitin proteins. Cleavage of the Ubiquitin precursors by deubiquitinating enzymes gives rise to identical Ubiquitin monomers each with a predicted molecular weight of 8.6 kDa. Conjugation of Ubiquitin to target proteins involves the formation of an isopeptide bond between the C-terminal glycine residue of Ubiquitin and a lysine residue in the target protein. This process of conjugation, referred to as ubiquitination or ubiquitylation, is a multi-step process that requires three enzymes: a Ubiquitin-activating (E1) enzyme, a Ubiquitin-conjugating (E2) enzyme, and a Ubiquitin ligase (E3). Ubiquitination is classically recognized as a mechanism to target proteins for degradation and as a result, Ubiquitin was originally named ATP-dependent Proteolysis Factor 1 (APF-1). In addition to protein degradation, ubiquitination has been shown to mediate a variety of biological processes such as signal transduction, endocytosis, and post-endocytic sorting.

Showing 1-8 out of 8 Ubiquitin 1 Products

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Human Ubiquitin/Ubiquitin+1 Antibody

IHC, WBMAB7011  
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Human Ubiquitin Antibody

WBA-1041  
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Human Ubiquitin+1 Antibody

IHC, WBMAB703 
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Human Ubiquitin+1 Antibody

WBAF703 
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Human Ubiquitin+1 Antibody

ELISA(Cap), WBMAB7031 
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Human Ubiquitin+1 Biotinylated Antibody

ELISA(Det), WBBAM7032 
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Human Ubiquitin+1 DuoSet ELISA

ELISADY7031  
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Recombinant Human Ubiquitin+1 Protein, CF

 703-UB 
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