VAP-B: Products

VAP-B (vesicle-associated membrane protein (VAMP)-associated protein B) is a ubiquitously expressed type IV transmembrane protein belonging to the VAP family. It is found in ER, Golgi and other membranes as a homodimer or a heterodimer with VAP-A. VAPs recruit FFAT proteins that mediate many of their effects on regulation of membrane transport, phospholipid biosynthesis, microtubule organization, and the unfolded protein response. VAPs also interact with some SNARE and viral proteins, notably hepatitis C virus (HCV), which requires VAB-B for its propagation. The P56S polymorphism of VAP-B is found in amylotrophic lateral sclerosis and causes formation of intracellular aggregates and increased ER-stress-induced death of motor neurons. It can also promote cleavage and secretion of soluble VAP-B, which can then function as a ligand for EPH receptors.

Showing 1-7 out of 7 VAP-B Products

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Human VAP-B Antibody

Flow, IHC, WBMAB58551 
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Rat VAP-B Antibody

IHC, WBMAB7329 
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Human VAP-B Antibody

IHC, WBAF5855 
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Human VAP-B Antibody

IHCMAB5855 
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Human VAP-B Alexa Fluor® 488-conjugated Antibody

FlowIC58551G 
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Human VAP-B PE-conjugated Antibody

FlowIC58551P 
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Recombinant Human VAP-B Protein, CF

 5855-VB 
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