VEGF R1, R2, R3: Products

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Showing 1-8 out of 8 VEGF R1, R2, R3 Products

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SU 5402


Potent FGFR and VEGFR inhibitor
330011  
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Axitinib


Potent VEGFR-1, -2 and -3 inhibitor
43502  
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Sunitinib malate


Potent VEGFR, PDGFRbeta and KIT inhibitor
37682  
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Human VEGF R1, R2, R3 PE-conjugated Antibody Sampler Pack


1 vial each of PE-conjugated anti-VEGF R1 (clone 49560), VEGF R2 (clone 89106), and VEGF R3 (clone 54733)
FlowFABSP3P 
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ZM 306416 hydrochloride


Inhibitor of VEGF receptor tyrosine kinase
24992  
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SU 4312


Potent inhibitor of VEGFR tyrosine kinase
14591  
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XL 184


Potent VEGFR inhibitor; also inhibits other RTKs
5422 
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AEE 788


Potent EGFR and VEGFR inhibitor
53181  
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