Vanilloid R1/TRPV1: Products

Vanilloid Receptor 1 (VR1) also known as TRPV1 (Transient Receptor Potential Vanilloid 1) and capsaicin receptor, is a 115 kDa integral membrane ion channel that has six transmembrane domains and contains intracellular N-and C-termini. Vanilloid Receptor 1 contributes to normal pain and temperature sensation and also has a sensory-effector function. By alternative splicing, at least three VR1 isoforms are known. The sequence of residues 4 - 21 of rat VR1 is 78% and 28% identical to that of mouse and human VR1, respectively.

Showing 1-26 out of 26 Vanilloid R1/TRPV1 Products

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(E)-Capsaicin


Prototypic vanilloid receptor agonist
046228  
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Rat Vanilloid R1/TRPV1 Antibody

IHCAF30661  
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Capsazepine


Vanilloid receptor antagonist; also activator of ENaCdelta
046437  
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Resiniferatoxin


Potent vanilloid receptor agonist
11374  
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AMG 9810


Potent and selective, competitive antagonist of TRPV1
23167  
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DIDS


Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor
45232  
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SB 366791


Potent, selective, competitive TRPV1 antagonist
16159  
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A 784168


Potent and selective TRPV1 antagonist
4319 
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JNJ 17203212


Reversible, competitive and potent TRPV1 antagonist
33612  
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5'-Iodoresiniferatoxin


Potent, silent TRPV1 antagonist
13629  
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OLDA


Potent, selective endogenous TRPV1 agonist
1641 
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BCTC


TRPV1 antagonist
3875 
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6'-Iodoresiniferatoxin


High affinity TRPV1 agonist/partial agonist
1556 
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PPAHV


Non-pungent vanilloid receptor agonist
1466 
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AMG 21629


Potent and selective TRPV1 antagonist
4330 
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SB 452533


Potent TRPV1 receptor antagonist
32651  
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6-Iodonordihydrocapsaicin


Potent, competitive vanilloid receptor antagonist
1975 
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PALDA


Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors
2203 
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Arachidonyl serotonin


Dual FAAH inhibitor/TRPV1 antagonist
2836 
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Olvanil


Potent vanilloid receptor agonist
09341  
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L-R4W2


TRPV1 antagonist peptide
1577 
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STEARDA


Endogenous lipid, active in vivo. Enhances effects of endovanilloids at TRPV1 receptors
2204 
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α-Spinasterol


TRPV1 antagonist; active in vivo
4729 
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MRS 1477


TRPV1 positive allosteric modulator
5246 
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AMG 517


Potent TRPV1 antagonist
5995 
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Vanilloid TRPV1 Receptor Tocriset™


Selection of 5 vanilloid TRPV1 receptor ligands (Cat. Nos. 0462, 0934, 1137, 0464 and 1615)
2181 
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