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Vitamin D BP: Products

TIGIT (T cell Immunoreceptor with Ig and ITIM domains), also called Vstm3, Vsig9,  and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins. TIGIT is expressed on NK cells and subsets of activated, memory and regulatory T cells, and particularly on follicular helper T cells within secondary lymphoid organs. It binds to CD155/PVR/Necl-5 and Nectin-2/CD112/PVRL2 on dendritic cells (DC) and endothelium. Binding of TIGIT by DC induces IL-10 release and inhibits IL-12 production. Ligation of TIGIT on T cells downregulates TCR-mediated activation and subsequent proliferation, while NK cell TIGIT ligation blocks NK cell cytotoxicity. CD155 and Nectin-2 also interact with DNAM-1/CD226 and CD96/Tactile, and TIGIT binding to CD155 can antagonize the effects of DNAM-1. Soluble TIGIT is able to compete with DNAM-1 for CD155 binding and attenuates T cell responses, while mice lacking TIGIT show increased T cell responses and susceptibility to autoimmune challenges.

Showing 1-10 out of 10 Vitamin D BP Products

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Human Magnetic Luminex Assay

LXSAHM25  
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Build your own with our Luminex Assay Customization Tool.

Human Vitamin D BP Quantikine ELISA Kit

ELISADVDBP0B17  
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Human Luminex Assay

LXSAH5  
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Build your own with our Luminex Assay Customization Tool.

Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B11  
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Mouse Vitamin D BP Antibody

SW, WBAF4188 
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Human Vitamin D BP DuoSet ELISA


Product is in the process of discontinuation and replaced by catalog # DY3778B-05.
ELISADY3778 
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Human Vitamin D BP DuoSet ELISA

DY3778B-05 
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Human Vitamin D BP Antibody

WBMAB3778 
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Quantikine Immunoassay Control Set 925 Human Vitamin D BP


For use with catalog number DVDBP0B
QC185B 
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Mouse Vitamin D BP DuoSet ELISA

ELISADY4188-05 
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