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ZNRF3: Products

The cell-surface transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) and its homologue ring finger 43 (RNF43) are negative feedback regulators of Wnt signaling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signaling by promoting the turnover of frizzled and LRP6. R-spondin may enhance Wnt signaling by inhibiting ZNRF3. ZNRF3 may be a target for therapeutic exploration.

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Recombinant Mouse ZNRF3 Fc Chimera Protein, CF

 8328-RF 
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Recombinant Human ZNRF3 Fc Chimera Protein, CF

 7994-RF 
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Human ZNRF3 (NP_001193927) VersaClone cDNA

RDC0508 
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