alpha-2A Adrenergic R/ADRA2A: Products

Alpha-2-adrenergic receptors, including ADRA2A, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both ADRA2A and ADRA2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

Showing 1-25 out of 25 alpha-2A Adrenergic R/ADRA2A Products

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Clonidine hydrochloride


alpha2 agonist. Also I1 ligand
06906  
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Dihydroergotamine mesylate


Partial alpha agonist. Non-selective
0475 
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Atipamezole hydrochloride


Selective alpha2 antagonist
29371  
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Yohimbine hydrochloride


Selective alpha2 antagonist
112717  
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Guanabenz acetate


alpha2 agonist. Also I2 selective ligand
08854  
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Agmatine sulfate


alpha2 ligand. Also imidazoline ligand
08421  
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Guanfacine hydrochloride


alpha2A agonist
10302  
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UK 14,304


alpha2 agonist
04253  
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Medetomidine hydrochloride


Potent, highly selective alpha2 agonist
51601  
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Rauwolscine hydrochloride


alpha2 antagonist
08912  
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BRL 44408 maleate


Selective alpha2A antagonist
11331  
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Nicergoline


alpha antagonist
06041  
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Dexmedetomidine hydrochloride


Potent, highly selective alpha2 agonist. Active isomer of medetomidine (Cat. No. 5160)
27493  
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RS 79948 hydrochloride


Potent, selective alpha2 antagonist
09871  
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Efaroxan hydrochloride


alpha2 antagonist and I1, I3 ligand
0792 
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Rilmenidine hemifumarate


alpha2 agonist. Also I1 ligand
07901  
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Idazoxan hydrochloride


alpha2 antagonist. Also I2 ligand
07932  
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SKF 86466 hydrochloride


Potent and selective alpha2 antagonist
3866 
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A 80426 mesylate


High affinity alpha2 antagonist. Also 5-HT uptake inhibitor
2341 
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UK 14,304 tartrate


alpha2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
2466 
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B-HT 933 dihydrochloride


Selective alpha2 agonist
27581  
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Dihydroergocristine mesylate


Partial alpha agonist. Non-selective
0474 
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Tizanidine hydrochloride


alpha2 agonist
3609 
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Human ADRA2A (AAF91441) VersaClone cDNA

RDC0256 
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Rat alpha-2A Adrenergic R/ADRA2A (NP_036871) VersaClone cDNA

RDC0818 
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