alpha-2C Adrenergic R/ADRA2C: Products

Alpha-2-adrenergic receptors, including ADRA2C, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C receptors that have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Mouse studies have revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

Showing 1-24 out of 24 alpha-2C Adrenergic R/ADRA2C Products

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Clonidine hydrochloride


alpha2 agonist. Also I1 ligand
06906  
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Yohimbine hydrochloride


Selective alpha2 antagonist
112717  
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Atipamezole hydrochloride


Selective alpha2 antagonist
29371  
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Guanabenz acetate


alpha2 agonist. Also I2 selective ligand
08854  
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Dihydroergotamine mesylate


Partial alpha agonist. Non-selective
0475 
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Medetomidine hydrochloride


Potent, highly selective alpha2 agonist
51601  
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RS 79948 hydrochloride


Potent, selective alpha2 antagonist
09871  
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Rauwolscine hydrochloride


alpha2 antagonist
08912  
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UK 14,304


alpha2 agonist
04253  
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Agmatine sulfate


alpha2 ligand. Also imidazoline ligand
08421  
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Dexmedetomidine hydrochloride


Potent, highly selective alpha2 agonist. Active isomer of medetomidine (Cat. No. 5160)
27493  
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Rilmenidine hemifumarate


alpha2 agonist. Also I1 ligand
07901  
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SKF 86466 hydrochloride


Potent and selective alpha2 antagonist
3866 
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Efaroxan hydrochloride


alpha2 antagonist and I1, I3 ligand
0792 
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Dihydroergocristine mesylate


Partial alpha agonist. Non-selective
0474 
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JP 1302 dihydrochloride


Potent and selective alpha2C antagonist
26661  
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A 80426 mesylate


High affinity alpha2 antagonist. Also 5-HT uptake inhibitor
2341 
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Tizanidine hydrochloride


alpha2 agonist
3609 
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Spiroxatrine


Potent alpha2C antagonist
06311  
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ST 91


alpha2 agonist, putative alpha2C agonist
26381  
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UK 14,304 tartrate


alpha2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
2466 
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Idazoxan hydrochloride


alpha2 antagonist. Also I2 ligand
07932  
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B-HT 933 dihydrochloride


Selective alpha2 agonist
27581  
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Human ADRA2C (NP_000674) VersaClone cDNA

RDC0258 
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