alpha-2C Adrenergic R/ADRA2C: Products

Alpha-2-adrenergic receptors, including ADRA2C, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C receptors that have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Mouse studies have revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

Showing 1-24 out of 24 alpha-2C Adrenergic R/ADRA2C Products

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Clonidine hydrochloride


α2 agonist. Also I1 ligand
06908
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Guanabenz acetate


α2 agonist. Also I2 selective ligand
08854
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Yohimbine hydrochloride


Selective α2 antagonist
112720
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Atipamezole hydrochloride


Selective α2 antagonist
29371
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Medetomidine hydrochloride


Potent, highly selective α2 agonist
51602
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UK 14,304


α2 agonist
04253
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Spiroxatrine


Potent α2C antagonist
06311
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Agmatine sulfate


α2 ligand. Also imidazoline ligand
08421
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RS 79948 hydrochloride


Potent, selective α2 antagonist
09872
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Dexmedetomidine hydrochloride


Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)
27495
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Rilmenidine hemifumarate


α2 agonist. Also I1 ligand
07901
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Dihydroergocristine mesylate


Partial α agonist. Non-selective
0474
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Dihydroergotamine mesylate


Partial α agonist. Non-selective
0475
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Efaroxan hydrochloride


α2 antagonist and I1, I3 ligand
0792
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Idazoxan hydrochloride


α2 antagonist. Also I2 ligand
07932
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Rauwolscine hydrochloride


α2 antagonist
08912
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A 80426 mesylate


High affinity α2 antagonist. Also 5-HT uptake inhibitor
2341
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UK 14,304 tartrate


α2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
2466
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ST 91


α2 agonist, putative α2C agonist
26381
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JP 1302 dihydrochloride


Potent and selective α2C antagonist
26661
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B-HT 933 dihydrochloride


Selective α2 agonist
27581
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Tizanidine hydrochloride


α2 agonist
3609
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SKF 86466 hydrochloride


Potent and selective α2 antagonist
3866
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Human ADRA2C (NP_000674) VersaClone cDNA

RDC0258 
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