beta-2 Adrenergic R/ADRB2: Products

ADRB2 is a member of the G protein-coupled receptor superfamily that is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. ADRB2 binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by ADRB2. Different polymorphic forms, point mutations, and/or downregulation of ADRB2 are associated with nocturnal asthma, obesity and type 2 diabetes.

Showing 1-10 out of 10 beta-2 Adrenergic R/ADRB2 Products

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ICI 118,551 hydrochloride


Very selective β2 antagonist/inverse agonist
082134  
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Salbutamol hemisulfate


β agonist (β2 > β1)
06342  
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Formoterol hemifumarate


Potent and selective β2 agonist
14487  
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Salmeterol xinafoate


Long-acting β2 agonist; bronchodilator
47124  
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Dobutamine hydrochloride


α1, β1 and β2 agonist
05152  
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Zinterol hydrochloride


Selective β2 agonist
10512  
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CGP 12177 hydrochloride


β3 partial agonist. β1/β2 antagonist.
11345  
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Procaterol hydrochloride


Potent β2 agonist
11024  
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Human ADRB2 (AAF20199) VersaClone cDNA

RDC0260 
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Human beta-2 Adrenergic R/ADRB2 (NP_000015) VersaClone cDNA

RDC0631 
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