cAMP: Products

cAMP (adenosine 3’5’-cyclic monophosphate) is a ubiquitous intracellular second messenger that mediates a diverse range of cellular processes in all organisms from bacteria to higher eukaryotes. It is converted from adenosine triphosphate (ATP) by adenylyl cyclases (ACs), and is inactivated by phosphodiesterases (PDEs) which catalyze its hydrolysis to 5’-AMP. In mammals, upon interaction with extracellular ligands, G protein coupled receptors (GPCRs) linked to Gαs activate the family of nine transmembrane ACs to increase intracellular cAMP. In contrast, GPCRs associated with Gαi/o inhibit the synthesis of cAMP by transmembrane ACs. cAMP binds and activates protein kinase A (PKA), the guanine nucleotide exchange factors Epac1/2, and cyclic nucleotide-gated ion channels. It can be released extracellularly where it is converted to adenosine by phosphodiesterases and nucleotidases.

Showing 1-10 out of 10 cAMP Products

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cAMP Parameter Assay Kit

ELISAKGE002B53  
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Mouse/Rat cAMP Parameter Assay Kit

ELISAKGE012B5  
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Dibutyryl-cAMP, sodium salt


Cell-permeable cAMP analog
11411  
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8-Bromo-cAMP, sodium salt


Cell-permeable cAMP analog
11407  
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cAMPS-Rp, triethylammonium salt


cAMP antagonist
13379  
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6-Bnz-cAMP sodium salt


Cell permeable cAMP analog
5255 
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cAMP Antibody

ICC/IFMAB21462  
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Parameter Immunoassay Control Set 764 for cAMP


For use with catalog numbers KGE002B, SKGE002B, PKGE002B
CtrlQC52 
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cAMPS-Sp, triethylammonium salt


Cell-permeable cAMP analog
13331  
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Parameter Immunoassay Control Set 764 for Mouse/Rat cAMP


For use with catalog number KGE012
CtrlQC53 
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