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cIAP-2/HIAP-1: Products

cIAP-2 (also known as MIHC and HIAP-1) is a member of the inhibitor of apoptosis (IAP) family of proteins that inhibit the proteolytic activity of mature caspases. cIAP-2 has 3 BIR (baculovirus inhibitor of apoptosis) domains, a RING finger domain, and a caspase recruitment domain (CARD). cIAP-2 inhibits caspases through the direct interaction of its BIR domain with the active caspase. Caspase activity may be restored through interactions with the Reaper like motif on mitochondrial proteins such as SMAC/Diablo or HtrA2/Omi. cIAP-2 is reported to be cleaved by HtrA2/Omi.

Showing 1-11 out of 11 cIAP-2/HIAP-1 Products

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Human cIAP-2/HIAP-1 Antibody

IHC, SW, WBAF81716  
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Human/Mouse cIAP-2/HIAP-1 Antibody

IHC, SW, WBMAB8172  
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Human/Mouse cIAP Pan-specific Antibody

SW, WBMAB34006  
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Human cIAP-2/HIAP-1 Biotinylated Antibody

WBBAF8171 
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Proteome Profiler Human Apoptosis Array Kit


Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
ARY00928  
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Recombinant Human cIAP-2 (HIAP-1) Protein, CF

 817-P21  
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AEG 40730 dihydrochloride


IAP antagonist; induces apoptosis
5330 
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AZD 5582 dihydrochloride


Dimeric Smac mimetic; potent IAP inhibitor
5141 
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UC 112


IAP and XIAP inhibitor; antitumor
5251 
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Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY027 
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Proteome Profiler Human NFkB Pathway Array Kit


Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
ARY029 
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