CD47: Products

CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a ubiquitous transmembrane protein that binds to SIRP family members on macrophages, neutrophils, and T cells. These interactions prevent macrophage-mediated clearance of healthy CD47-expressing cells and promote immune cell transmigration across the vascular endothelium. CD47 associates in cis with Fas on T cells and enhances Fas-mediated apoptosis; its ligation promotes T cell anergy and dampens Th1 immune responses. CD47 also associates in cis with several Integrins which can positively or negatively modulate Integrin-mediated function. CD47 binding by Thrombospondin-1 inhibits the angiogenic and vasorelaxant effects of nitric oxide. On dendritic cells and myeloma cells, CD47 ligation by TSP-1 induces giant cell formation and osteoclast differentiation.

Showing 1-19 out of 19 CD47 Products

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Recombinant Human CD47 Fc Chimera Protein, CF

 4670-CD2  
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Recombinant Mouse CD47 Fc Chimera Protein, CF

 1866-CD1  
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Human CD47 Antibody

B/N, CyTOF-ready, Flow, IHC, WBAF46702  
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Mouse/Rat CD47 N-terminal IgV-like Extracellular Domain Antibody

IHC, WBAF18661  
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Human CD47 Antibody

B/N, CyTOF-ready, FlowMAB4670 
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Mouse CD47 N-terminal IgV-like Extracellular Domain Biotinylated Antibody

Flow, IHC, WBBAF1866 
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Human CD47 APC-conjugated Antibody

FlowFAB4670A1  
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Recombinant Human CD47 His-tag Protein, CF

 9396-CD 
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Human CD47 DuoSet ELISA

ELISADY4670-051  
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Human CD47 PE-conjugated Antibody

FlowFAB4670P 
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Human CD47 Alexa Fluor® 488-conjugated Antibody

FlowFAB4670G 
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Human CD47 Alexa Fluor® 405-conjugated Antibody

FlowFAB4670V 
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Human CD47 (NP_001768) VersaClone cDNA

RDC1523 
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Cynomolgus Monkey CD47 (XP_015301971) VersaClone cDNA

RDC1832 
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Human CD47 Alexa Fluor® 700-conjugated Antibody

FlowFAB4670N 
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Human CD47 Alexa Fluor® 647-conjugated Antibody

FlowFAB4670R 
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Human CD47 Alexa Fluor® 750-conjugated Antibody

FlowFAB4670S 
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Human CD47 Alexa Fluor® 594-conjugated Antibody

FlowFAB4670T 
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Human CD47 Alexa Fluor® 350-conjugated Antibody

FlowFAB4670U 
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