eIF4E: Products

Eukaryotic initiation factors (eIFs) are heterotrimeric initiation complexes that form on the ribosome during protein synthesis. Each eIF serves a distinct function during protein synthesis to help attach, assemble, and drive the ribosome along the mRNA. eIF4E interacts with the 7-methyl-GTP cap structure to facilitate the initiation and rate of translation of mRNA. Together with eIF4G and eIF4A, it forms the eIF4F complex. eIF4E activity has been shown to play a role in cell cycle progression, tumorigenesis, embryonic development, nuclear export and synaptic plasticity.

Showing 1-4 out of 4 eIF4E Products

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Human/Mouse/Rat eIF4E Antibody

ICC/IF, WBMAB3228 
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4EGI-1


Inhibitor of eIF4E:eIF4G interaction
4800 
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Ribavirin


Antiviral guanosine analog; blocks eIF4E activity
4501 
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4E1RCat


Protein translation inhibitor; blocks eIF4F subunit interaction
42151  
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