sFRP-1: Products

sFRP-1 (Secreted Frizzled Related Protein-1), also known as SARP-2, FRP, and FrzA, is a secreted protein that binds to Wnt-1, -2, -3a, and -4 and prevents their activation of canonical beta-Catenin signaling. sFRP-1 is upregulated in the ischemic heart where it limits inflammation and the severity of tissue damage following myocardial infarction. During angiogenesis it induces endothelial cell migration, tube formation, and vessel formation. sFRP-1 is expressed by bone marrow stromal cells and osteoclasts. It binds to TRANCE/RANK Ligand, inhibits osteoclast and osteoblast formation and survival, and inhibits the formation of trabecular bone. sFRP-1 additionally restricts kidney tubule formation, the inflammatory activation of leukocytes, early B lymphoid progression, and vitreous fluid outflow in the eye.

Showing 1-11 out of 11 sFRP-1 Products

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Recombinant Human sFRP-1 Protein, CF

Bioactivity5396-SF12  
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Human sFRP-1 Antibody

ICC/IF, IHC, WBAF13846  
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Recombinant Human sFRP-1 (Histidine-tagged) Protein


A New and Improved rhsFRP-1 is Available! It has a lower endotoxin spec, ~3 fold better activity, and no tag!
New Product 5396-SF
Bioactivity1384-SF8  
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Recombinant Human sFRP-1 (Histidine-tagged) Protein, CF


A New and Improved rhsFRP-1 is Available! It has a lower endotoxin spec, ~3 fold better activity, and no tag!
New Product 5396-SF
Bioactivity1384-SF/CF8  
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Recombinant Mouse sFRP-1 Protein

Bioactivity9019-SF3  
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Recombinant Mouse sFRP-1 Protein, CF

Bioactivity9019-SF/CF3  
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WAY 316606 hydrochloride


Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling
4767
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Recombinant Mouse Wnt-1/sFRP-1 Complex Protein

Bioactivity9765-WN 
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Human sFRP-1 Biotinylated Antibody

WBBAF1384 
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Human sFRP-1 (AAB70793) VersaClone cDNA

RDC2351 
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Mouse sFRP-1 (AAH24495) VersaClone cDNA

RDC2375 
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