1 result for "5-HT1 Receptor Agonists" in Products

5-HT1 Receptor Agonists

The serotonin 5-HT1A receptor was the first 5-HT receptor to be fully sequenced and the human gene encoding this receptor has been localized to chromosome 5 (5q11.2-q13).

5-HT1A receptor binding sites are located primarily in limbic brain areas, notably the hypothalamus, lateral septum, cortical areas and the mesencephalic raphe nuclei. 5-HT1A receptor ligands with agonist activity possess antianxiety, antidepressant, antiaggressive, and perhaps anticraving, anticataleptic, antiemetic, and neuroprotective properties.

Highly potent D2-like antagonist; also 5-HT1A agonist

Alternate Names: YM 09151,YM 09151-2
Chemical Name: cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide
Purity: ≥98%
Highly potent D2-like antagonist; also 5-HT1A agonist
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