Active Degraders: Products

SRC-1 peptide-based PROTAC®; active in vivo

Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR

Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR

Potent tropomyosin receptor kinase (TRK) degrader

Selective BRAF-V600E protein Degrader (uSMITE™)

Potent and selective trivalent BET Bromodomain Degrader (PROTAC®)

Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity

Potent BRAF PROTAC®

Negative control for SJF 0628 (Cat. No. 7463)

Selective CDK12 PROTAC® Degrader

Potent PARP1 Degrader (PROTAC®)

Potent GSK3 Degrader (PROTAC®)

Selective JAK2 Degrader (PROTAC®)

JQ1-maleimide functionalized probe; induces proteasomal degradation of BRD4

Mitochondrial targeting AUTAC Degrader

Potent and selective LCK Degrader (PROTAC®)

Potent and selective JAK2/3 Degrader (PROTAC®)

Potent and selective BRAFV600E Degrader (PROTAC®)

Potent and selective CDK2 Degrader (PROTAC®)

Selective HyT-based degrader of the CDK9-cyclin T1 complex

Polycomb repressive complex 2 (PRC2) Degrader PROTAC®

Potent and selective focal adhesion kinase (FAK) degrader

Aurora A Degrader (PROTAC®)

Potent and selective nicotinamide phosphoribosyl transferase (NAMPT) Degrader (PROTAC®)

Potent and selective HDAC4 Degrader (PROTAC®)

Selective and potent TAG Degrader for auxin-inducible degron 2 system; 5-Ph-IAA analog

Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC®)

Selective STING Degrader (PROTAC®)