Apoptosis Inducer Compounds: Products

"Apoptosis Inducer Compounds" has 45 results in Products.
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ABT 737 

Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

Bioymifi 

DR5 (TRAIL receptor) agonist; induces apoptosis

MRT 68921 dihydrochloride 

Potent ULK inhibitor; inhibits autophagy

Chaetoglobosin A 

Antibiotic; selectively induces apoptosis of CLL cells

Oleanolic acid 

Selective GPBA receptor (TGR5) partial agonist

CHMFL-FLT3-122 

Potent and selective FLT3 inhibitor

SMBA 1 

High affinity and selective activator of Bax

Cladribine 

Deoxyadenosine analog; pro-apoptotic

UC 112 

IAP and XIAP inhibitor; antitumor

CFM 4 

CARP-1 mimetic; proapoptotic

PCI 34051 

Potent and selective HDAC8 inhibitor

iMDK 

Suppressor of MDK expression; inhibits PI 3-K signaling

FK 866 hydrochloride 

Potent and non-competitive NAMPT inhibitor; induces apoptosis and autophagy

NSC 687852 

Inhibitor of UCHL5 and USP14

BAM 7 

Selective Bax activator; induces Bax-mediated apoptosis

Apicidin 

Potent histone deacetylase inhibitor

Plumbagin 

Induces G2/M cell cycle arrest; anticancer

Piperlongumine 

Induces apoptosis; increases p53 and ROS levels in cancer cells

Kaempferol 

Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter

CHM 1 

Potent antitumor agent; inducer of apoptosis

2-Methoxyestradiol 

Apoptotic and antiangiogenic agent

Mitomycin C 

DNA cross-linking antitumor agent

Cyclophosphamide 

Alkylating agent; chemotherapeutic

Oncrasin 1 

Induces abnormal nuclear aggregation of PKCι; proapoptotic

AT 101 

Downregulates Bcl-2 and Mcl-1; pro-apoptotic

TW 37 

Bcl-2 inhibitor; induces apoptosis

Apoptosis Activator 2 

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

Streptozocin 

DNA alkylator; antitumor and induces diabetes

Actinomycin D 

Inhibits RNA polymerase

Oxaliplatin 

DNA cross-linking antitumor agent

Curcumin 

Antitumor, anti-inflammatory and antioxidant

Betulinic acid 

Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist

Narciclasine 

Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression

Gambogic acid 

Apoptosis inducer. Activates caspases and inhibits Bcl-2 family proteins

Bendamustine hydrochloride 

Cytostatic agent; exhibits DNA alkylating and purine analog properties

Embelin 

Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor

Carboplatin 

DNA cross-linking antitumor agent

Deguelin 

Anticancer and antiviral agent; chemopreventive and pro-apoptotic

C 75 

Potent fatty acid synthase inhibitor; proapoptotic

Cisplatin 

Potent pro-apoptotic anticancer agent; activates caspase-3

Fludarabine 

Purine analog; inhibits DNA synthesis

Triptolide 

Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

2,3-DCPE hydrochloride 

Selectively induces cancer cell apoptosis

Temozolomide 

DNA-methylating antitumor agent

Doxorubicin hydrochloride 

Antitumor antibiotic agent. Inhibits DNA topoisomerase II
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