27 results for "Compounds for Induced Pluripotent Stem Cells" in Products
Compounds for Induced Pluripotent Stem Cells
Reprogramming of cells refers to the regression of a specialized cell to a simpler state, resulting in cells with stem-like properties, or the direct transformation of one specialized cell type into another, which is also known as transdifferentiation. The process of cells regressing to a stem cell-like state occurs naturally, mostly for repair and regeneration in aged or damaged tissues, being also known as dedifferentiation. Reprogramming can be artificially induced using a combination of ...
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥99% |
Highly selective GSK-3 inhibitor; acts as Wnt activator
| Alternate Names: | CHIR99021,CT99021 |
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥98% |
EZH2 histone methyltransferase inhibitor
| Alternate Names: | DZNep,NSC 617989,HY-12186 |
| Chemical Name: | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity: | ≥98% |
Selective inhibitor of TGF-βRI, ALK4 and ALK7
| Chemical Name: | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
| Purity: | ≥98% |
PORCN inhibitor; inhibits Wnt processing and secretion
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% |
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% |
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
| Chemical Name: | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥99% |
Potent and selective inhibitor of TGF-βRI
| Alternate Names: | E-616452,SJN 2511,ALK5 Inhibitor II |
| Chemical Name: | 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine |
| Purity: | ≥99% |
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide |
| Purity: | ≥99% |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs
| Chemical Name: | N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide |
| Purity: | ≥98% |
Inhibitor of Hedgehog (Hh) signaling
| Chemical Name: | (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol |
| Purity: | ≥97% |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
p53 inhibitor. Also aryl hydrocarbon receptor agonist
| Chemical Name: | 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide |
CK1 inhibitor
| Chemical Name: | N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride |
| Purity: | ≥99% |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% |
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% |
Histone deacetylase inhibitor
| Chemical Name: | Butanoic acid sodium salt |
Irreversible inhibitor of LSD1; also inhibits MAO
| Alternate Names: | 2-PCPA |
| Chemical Name: | (±)-trans-2-Phenylcyclopropylamine hydrochloride |
| Purity: | ≥98% |
Non-nucleoside DNA methyltransferase inhibitor
| Chemical Name: | N-Phthalyl-L-tryptophan |
| Purity: | ≥98% |
GLP and G9a inhibitor
| Chemical Name: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
| Purity: | ≥98% |
DNA methyltransferase inhibitor
| Chemical Name: | 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one |
| Purity: | ≥98% |
GSK-3β inhibitor; also inhibits cdks
| Chemical Name: | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
| Purity: | ≥98% |
ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
| Chemical Name: | (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol |
| Purity: | ≥98% |
SCD-1 inhibitor
| Alternate Names: | NSC 14613 |
| Chemical Name: | 4-Pyridinecarboxylic acid 2-phenylhydrazide |
| Purity: | ≥99% |
