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Antifibrotic agent; regulates cytokine levels in vivo
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
Dye used as counterstain in histochemistry; also potent inhibitor of L-glutamate uptake into synaptic vesicles; also inhibits MIF
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
Reported macrophage migration inhibitory factor (MIF) inhibitor
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
Cereblon binder; also TNF-α inhibitor and antiangiogenic
Binds cereblon; also TNF-α synthesis inhibitor
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
Selective Syk kinase inhibitor
Immunomodulator; reduces production of pro-inflammatory cytokines
Macrophage migration inhibitory factor (MIF) inhibitor
Immunomodulatory and antitumor compound
Stimulated by IFN-γ; marker of immune activation
Active metabolite binds CPSF3; Pro-drug
Potent and selective IRAK4 inhibitor
gp130 agonist; brain penetrant and neuroprotectant
NLRP3 inflammasome inhibitor
TIR-TIR interaction inhibitor
gp130 modulator; activates JAK/STAT signaling
Inhibitor of pro-inflammatory mediator release from mast cells
TRAF6-Ubc13 interaction inhibitor
Innate defence regulator peptide