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Dkk-1: Products
Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.
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Recombinant Mouse Dkk-1 (Histidine-tagged) Protein
A New and Improved rm Dkk-1 is Available! It has a lower endotoxin specification, ~5 fold better activity, and no tag!
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