FGF basic: Products

FGF basic (FGF-2) is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic binds to FGF R1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGF R1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.

 

"FGF basic" has 4 results in Products.
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Proteome Profiler Human Angiogenesis Array Kit

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Proteome Profiler Human XL Cytokine Array Kit

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Proteome Profiler Human XL Oncology Array

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Proteome Profiler Human Adipokine Array Kit

Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
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