12 results for "iPSC Generation" in Products

iPSC Generation Products

Highly selective GSK-3 inhibitor; acts as Wnt activator

GMP Version Available: TB4423-GMP
GMP
Alternate Names: CHIR99021,CT99021
Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥98%
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)
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EZH2 histone methyltransferase inhibitor

Alternate Names: DZNep,NSC 617989,HY-12186
Chemical Name: (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride
Purity: ≥98%
EZH2 histone methyltransferase inhibitor
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Potent and selective inhibitor of TGF-βRI

Alternate Names: E-616452,SJN 2511,ALK5 Inhibitor II
Chemical Name: 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
Purity: ≥99%
Potent and selective inhibitor of TGF-βRI
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Potent inhibitor of MEK1/2

Alternate Names: PD325901
Chemical Name: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
Purity: ≥99%
Potent inhibitor of MEK1/2
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ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs

Chemical Name: N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
Purity: ≥98%
ROCK inhibitor ; improves the efficiency of fibroblast reprogramming and induction of iPSCs
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Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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Irreversible inhibitor of LSD1; also inhibits MAO

Alternate Names: 2-PCPA
Chemical Name: (±)-trans-2-Phenylcyclopropylamine hydrochloride
Purity: ≥98%
Irreversible inhibitor of LSD1; also inhibits MAO
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Non-nucleoside DNA methyltransferase inhibitor

Chemical Name: N-Phthalyl-L-tryptophan
Purity: ≥98%
Non-nucleoside DNA methyltransferase inhibitor
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GLP and G9a inhibitor

Chemical Name: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride
Purity: ≥98%
GLP and G9a inhibitor
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DNA methyltransferase inhibitor

Chemical Name: 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Purity: ≥98%
DNA methyltransferase inhibitor
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GSK-3β inhibitor; also inhibits cdks

Chemical Name: 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Purity: ≥98%
GSK-3β inhibitor; also inhibits cdks
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Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO

Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥97%
Sterile-filtered 10mM solution of CHIR 99021 pre-dissolved in water
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