Nav1.8: Products

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Ranolazine dihydrochloride 

Antianginal, activates pyruvate dehydrogenase


Inhibitor of neuronal NaV channels; anticonvulsant

Flecainide acetate 

Cardiac Na+ channel blocker. Antiarrhythmic

Ambroxol hydrochloride 

Na+ channel blocker

Mexiletine hydrochloride 

Na+ channel blocker; antiarrhythmic agent


Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)

A 803467 

Selective NaV1.8 channel blocker


NaV blocker; neuroprotective

A 887826 

Potent voltage-dependent NaV1.8 channel blocker

PF 04885614 

Potent and selective NaV1.8 channel blocker; active in vivo
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