Secretase Inhibitors: Products

Many membrane proteins also occur as in soluble forms due to proteolytic cleavage by secretases. alpha-, beta-, and gamma-secretases are best known for their cleavage of APP, the protein precursor of amyloid beta peptide (A beta), a major component of Alzheimer's disease plaques.

"Secretase Inhibitors" has 12 results in Products.
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DAPT

γ-secretase inhibitor

DBZ

γ-secretase inhibitor; inhibits Notch pathway

L-685,458

Potent and selective γ-secretase inhibitor

Compound W

γ-secretase inhibitor

JLK 6

Inhibitor of γ-secretase-mediated βAPP processing

BMS 299897

Potent γ-secretase inhibitor

MRK 560

γ-secretase inhibitor; attenuates amyloid plaque deposition

Begacestat

γ-secretase inhibitor; lowers Aβ40 and Aβ42 levels

Flurizan

γ-secretase inhibitor; lowers Aβ42 levels in vitro

PF 3084014 hydrobromide

Potent γ-secretase inhibitor

Compound E

γ-secretase inhibitor; induces neuronal differentiation

DAPT

DAPT synthesized to cGMP guidelines
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