Secretase Inhibitors: Products

Many membrane proteins also occur as in soluble forms due to proteolytic cleavage by secretases. alpha-, beta-, and gamma-secretases are best known for their cleavage of APP, the protein precursor of amyloid beta peptide (A beta), a major component of Alzheimer's disease plaques.

"Secretase Inhibitors" has 13 results in Products.
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DAPT 

γ-secretase inhibitor; induces neuronal differentiation

DBZ 

γ-secretase inhibitor; inhibits Notch pathway

L-685,458 

Potent and selective γ-secretase inhibitor

Compound E 

γ-secretase inhibitor; induces neuronal differentiation

Compound W 

γ-secretase inhibitor

JLK 6 

Inhibitor of γ-secretase-mediated βAPP processing

BMS 299897 

Potent γ-secretase inhibitor

MRK 560 

γ-secretase inhibitor; attenuates amyloid plaque deposition

Begacestat 

γ-secretase inhibitor; lowers Aβ40 and Aβ42 levels

Flurizan 

γ-secretase inhibitor; lowers Aβ42 levels in vitro

PF 3084014 hydrobromide 

Potent γ-secretase inhibitor

Avagacestat 

Highly potent γ-secretase inhibitor; orally bioavailable

DAPT 

DAPT synthesized to cGMP guidelines
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