Key Product Details

Species Reactivity

Mouse

Applications

ELISA

Label

CoraFluor 1

Antibody Source

Monoclonal Rat IgG2A Clone # 352802.113
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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse ASGPR1
Ser60-Asn284
Accession # NP_033844

Specificity

Detects mouse ASGPR1 in direct ELISAs.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Scientific Data Images for ASGPR1 Antibody (352802.113) [CoraFluor™ 1]

ASGPR1 Antibody (352802.113) [CoraFluor™ 1]

Product Feature: CoraFluor Probes for TR-FRET

CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.

Applications for ASGPR1 Antibody (352802.113) [CoraFluor™ 1]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product MAB27551. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: ASGR1/ASGPR1

Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specificallyremoved from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated(galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubulesto an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to thecell surface and the ligand is transported to the lysosomes for degradation. (provided by RefSeq)

Long Name

Asialoglycoprotein Receptor 1

Alternate Names

ASGPR1, CLEC4H1, MHL1, RHL1

Additional ASGR1/ASGPR1 Products

Product Documents for ASGPR1 Antibody (352802.113) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ASGPR1 Antibody (352802.113) [CoraFluor™ 1]

Sold for research purposes only under agreement from Massachusetts General Hospital, US Patent No. 12,134,721. A license is required for development of new commercial assay platforms (e.g., microarrays, microfluidics), diagnostic use or other unlicensed uses. Please contact Technical Support for further details: techsupport@bio-techne.com.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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